Effect curve

MPH IR: what a typical day looks like

Onset around 0.5h, peak around 1.9h, lasting about 4.5h. These are population averages, not a prediction for you.

Typical MPH IR curve

Population average for a dose at 8am. Yours will differ, and that gap is what logging shows.

8am12pm4pm8pmTrack your own MPH IR curve

How long does MPH IR take to work?

Population averages put onset at roughly 0.5 hours after the dose. Timing varies with food, formulation and the person.

How long does MPH IR last?

Typically about 4.5 hours, with the strongest effect around 1.9 hours. Your own duration may be shorter or longer.

Why do I feel a crash on MPH IR?

MPH IR is a short-acting formulation, and a sharper wear-off or rebound is commonly reported as it fades. Logging how you feel at set times shows whether the dip is a pattern worth raising with your prescriber.

General information, not medical advice. Titrate never recommends a dose; talk to your prescriber about changes.

Sources