Effect curve
Guanfacine: what a typical day looks like
Onset around 1h, peak around 5h, lasting about 18h. These are population averages, not a prediction for you.
Typical Guanfacine curve
Population average for a dose at 8am. Yours will differ, and that gap is what logging shows.
How long does Guanfacine take to work?
Population averages put onset at roughly 1 hour after the dose. Timing varies with food, formulation and the person.
How long does Guanfacine last?
Typically about 18 hours, with the strongest effect around 5 hours. Your own duration may be shorter or longer.
Why do I feel a crash on Guanfacine?
Guanfacine is built to release gradually, but some people still notice a drop as it wears off. Logging how you feel at set times shows whether the dip is a pattern worth raising with your prescriber.
General information, not medical advice. Titrate never recommends a dose; talk to your prescriber about changes.